The first meta-analysis worth noting collected the data from 10 randomized trials comprising 1376 participants in total.  After analyzing the research, a key relationship emerged between dietary carbs and blood sugar levels. In short, the researchers described their finding thus: “the greater the carbohydrate restriction, the greater glucose lowering…” 
Adequate food records were available for analysis in a proportion of participants at each of the 4 timepoints (Table (Table2).2). Participants completed food records at a mean of 2.5 and a median of 3 timepoints. In general, comparing baseline to subsequent timepoints, mean carbohydrate intake decreased substantially and energy intake decreased moderately while protein and fat intake remained fairly constant.
People claiming huge benefits of these supplements – despite the lack of solid scientific support – may sometimes have a financial reason to believe in the supplements. Some of these products are sold under a multi-level marketing arrangement, where sales people are paid based on commission. For example, the company Prüvit sells drinkable ketones, called KETO//OS with a multi-level marketing structure.