A study with an intent-to-treat prospective design was published in 1998 by a team from the Johns Hopkins Hospital and followed-up by a report published in 2001. As with most studies of the ketogenic diet, there was no control group (patients who did not receive the treatment). The study enrolled 150 children. After three months, 83% of them were still on the diet, 26% had experienced a good reduction in seizures, 31% had had an excellent reduction and 3% were seizure-free.[Note 7] At twelve months, 55% were still on the diet, 23% had a good response, 20% had an excellent response and 7% were seizure-free. Those who had discontinued the diet by this stage did so because it was ineffective, too restrictive or due to illness, and most of those who remained were benefiting from it. The percentage of those still on the diet at two, three and four years was 39%, 20% and 12% respectively. During this period the most common reason for discontinuing the diet was because the children had become seizure-free or significantly better. At four years, 16% of the original 150 children had a good reduction in seizure frequency, 14% had an excellent reduction and 13% were seizure-free, though these figures include many who were no longer on the diet. Those remaining on the diet after this duration were typically not seizure-free but had had an excellent response.
Think of it as intermittent fasting 2.0 – only a bit more complicated. Ready? Here goes. There are three windows: one to get you started, one to help you reach your goal weight and a maintenance plan. You eat within a 12-hour, 14-hour or 16-hour window depending on which phase you’re in. But what you eat counts, too. The ‘green light’ lists of foods changes with every phase. Still there?
The ketogenic diet is not a benign, holistic or natural treatment for epilepsy; as with any serious medical therapy, there may be complications. These are generally less severe and less frequent than with anticonvulsant medication or surgery. Common but easily treatable short-term side effects include constipation, low-grade acidosis and hypoglycaemia if there is an initial fast. Raised levels of lipids in the blood affect up to 60% of children and cholesterol levels may increase by around 30%. This can be treated by changes to the fat content of the diet, such as from saturated fats towards polyunsaturated fats, and, if persistent, by lowering the ketogenic ratio. Supplements are necessary to counter the dietary deficiency of many micronutrients.
Similar to Greek yogurt, research has shown eating eggs for breakfast can make you feel more full and help you eat fewer calories throughout the day, meaning they’re quite the secret weapon for weight loss. Nutritionally speaking, one large hard-boiled egg (about 50 grams) contains less than one gram of carbs and remains an excellent source of protein. Eggs are also loaded with amino acids, antioxidants, and healthy fats.
Several comprehensive studies and meta-analyses have demonstrated that after a few months or even a year of a low carb diet versus a moderate/high carb diet, there are no significant differences in the amount of weight lost (2,3,4,5). I will say, however, most of these diets are NOT keto and are simply lower carb (i.e. 20%). Also, long-term effects (beyond 1 year) are not often studied due to budgetary constraints, so interpret results as you wish.
While the ketogenic diet is straightforward, it does require careful monitoring. You should begin by having your doctor check your blood glucose and ketone levels. Once you’ve been on the diet for some time and your body has adjusted to using fat for fuel, it’s still a good idea to see your doctor once a month for testing and to determine if your medications need any adjustments. And, even though you will most likely see your symptoms improve on this diet, be sure to regularly monitor your blood glucose at home, ideally before and after meals.
If you are interested in trying out a ketogenic diet, it’s important to do your research about how to make sure to obtain adequate nutrition and also to be prepared to adjust (or have your healthcare provider help you to adjust) your medication doses. Many people find that their insulin sensitivity changes after starting a ketogenic diet, so it is very important to be on the lookout for changes in blood glucose trends to determine if treatment needs to be adapted.
Hi Stacey, I can’t give medical advice and definitely recommend following your doctor’s recommendations. You can ask him/her if low carb would be better suited for you. Also, you may want to double check with him/her if the kidney concern was related to high protein, because that is a common misconception about keto – it is not a high protein diet/lifestyle.
Speaking of flavonoids, the waist-whittling compounds also exist in higher concentrations in red fruits such as watermelon, Pink Lady apples, and plums, meaning they also have the power to induce weight loss. In fact, a 2016 study in the journal BMJ found that people who eat a diet rich in flavonoid-heavy food tend to gain less weight, which could be promising seeing as many people tend to put on pounds as they age. In addition, anthocyanin, a specific flavonoid compound that gives red fruits their color, has been shown to reduce fat-storage genes.
What the expert says: ‘Like with atkins, you will lose weight quickly. The ketogenic diet is used in medicine, but under strict supervision and for set periods of time, so with appropriate support it can be safe in the short to medium term. The brain does use glucose as its fuel of choice, so ‘brain fog’ lethargy are common side effects. You’ll known when your body is running off ketones by your breath – it’s known as ‘keto breath’, and it’s bad. It also can affect your ability to exercise by due to a lack of quickly accessible energy.
On day 1, lunch is 3 cups of spinach topped with 3 ounces of salmon or sardines; the greens are loaded with vitamins A and K, plus iron, while the fish supplies protein and omega-3 fats. Include some chopped veggies on your salad, like tomato, broccoli and bell pepper for fiber and vitamin C to help you absorb the iron. Have a salad again on day 5, but use romaine lettuce this time, and substitute cannellini beans for your protein and choose cucumber, carrots and asparagus tips as veggies. Opt for olive oil and red wine or balsamic vinegar for your dressing.
Keep a food diary. In it, record your current daily eating habits. Write down what you eat for every meal of the day, and take note if you skip a meal. If you regularly skip breakfast, jot this down as well. Also write down any snacks you eat, even if you do this mindlessly - say, while watching TV. This diary will allow you to see where you stand right now in terms of eating practices and where you can start to make changes.